Featured Affiliate

Jillian C. Strayhorn

Dr. Strayhorn is the Associate Director of cadio. Her research focuses on developing, testing, and applying methods for decision-making based on the empirical results of optimization trials.

Featured Event

Upcoming Webinar: December 6th

Join our last webinar of the year, held on Wednesday December 6th at 1pm EST, to get your intervention optimization questions answered by the cadio team. Head to our Events page to sign up.

All News

Welcome to cadio!

Center Director, Linda Collins, and Associate Director, Kate Guastaferro, announce the official launch of cadio!

Further Learning

Whether you are looking for additional support as you prepare a grant proposal involving MOST or practical information helpful in managing your optimization trial, this section provides resources for a deeper dive into intervention optimization.

REDCap with Most

The goal of this manual is to show how one might setup a REDCap project to support a research study with multiple conditions, such as factorial experiments common in the Multiphase Optimization Strategy (MOST) framework.

Informal introduction to factorial experimental designs

The purpose of this page is to clarify some concepts, notation, and terminology related to factorial experimental designs, and to compare and contrast factorial experiments to randomized controlled trials (RCTs). A more in-depth introduction can...


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