Free Software

Download free software to help you power a factorial optimization trial.

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Recommended Reading

This section highlights a few implementations of MOST; provides readings that may be helpful in selecting an experimental design, conducting analyses from optimization trials, and implementing optimization trials; and lists recent articles on intervention optimization methods.

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Frequently Asked Questions

This section clarifies some of the more common misconceptions about intervention optimization, factorial experiments, and more.

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Further Learning

Whether you are looking for additional support as you prepare a grant proposal involving MOST or practical information helpful in managing your optimization trial, this section provides resources for a deeper dive into intervention optimization.

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Videos

Here you will find recorded videos introducing MOST for different audiences – new investigators, biostatisticians, and reviewers.

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