Online Courses

Our self-directed online courses, hosted through Coursera (, are available at no cost. CADIO often uses these asynchronous courses as the foundation for synchronous training opportunities.


We offer regular synchronous training workshops throughout the year. These workshops require a brief application as places are limited. Participants may be expected to have completed a corresponding asynchronous course ahead of time, and will be expected to participate in activities that require advance preparation.

Further Learning

Whether you are looking for additional support as you prepare a grant proposal involving MOST or practical information helpful in managing your optimization trial, this section provides resources for a deeper dive into intervention optimization.

REDCap with Most

The goal of this manual is to show how one might setup a REDCap project to support a research study with multiple conditions, such as factorial experiments common in the Multiphase Optimization Strategy (MOST) framework.

Informal introduction to factorial experimental designs

The purpose of this page is to clarify some concepts, notation, and terminology related to factorial experimental designs, and to compare and contrast factorial experiments to randomized controlled trials (RCTs). A more in-depth introduction can...


Join the CADIO Mailing List

Keep up to date with the latest news, events, online courses, and resources from CADIO.