Can I expect reviewers of grant proposals to understand MOST? If not, how should I handle this in the application? There is not enough room to provide a lot of background.

I work in the prevention field, in which the horizon on the outcome is very far away. How can I optimize under these circumstances? It seems like it would take decades.

I have conducted the preparation phase and now wish to write an R01 application. Should I propose to complete both the optimization and evaluation phases, or only the optimization phase?

I am a junior scientist who does not yet have any training in MOST, but see intervention optimization as essential to my research in the coming years. Do you think it’s possible to obtaining training in MOST via a K01 or similar?

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