Intervention Optimization’s 20th Anniversary

From the desk of Director Linda Collins: "In this commentary, I reflect on the evolution of intervention optimization from that first publication to today, and on what the future could hold if the intervention science field continues to adopt the optimization paradigm." Read more in the Annals of Behavioral Medicine.

Dear Caddy…

How would you respond if, in a summary statement, one of the reviewers said that MOST can no longer be considered innovative? Sincerely, Asking for a Friend   Read the answer here.  

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Spring 2025 Webinar Series: Coming Soon

Our Spring 2025 Webinar Series will follow a new Friday schedule and kick off on February 7th. Head to our Events page to learn more and sign up.

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Dear Caddy…

Dear Caddy, How would you respond if, in a summary statement, one of the reviewers said that MOST can no longer be considered innovative? Sincerely, Asking for a Friend Dear Asking, This comes down to...

Welcome to cadio!

Center Director, Linda Collins, and Associate Director, Kate Guastaferro, announce the official launch of cadio!

Further Learning

Whether you are looking for additional support as you prepare a grant proposal involving MOST or practical information helpful in managing your optimization trial, this section provides resources for a deeper dive into intervention optimization.

REDCap with Most

The goal of this manual is to show how one might setup a REDCap project to support a research study with multiple conditions, such as factorial experiments common in the Multiphase Optimization Strategy (MOST) framework.

Informal introduction to factorial experimental designs

The purpose of this page is to clarify some concepts, notation, and terminology related to factorial experimental designs, and to compare and contrast factorial experiments to randomized controlled trials (RCTs). A more in-depth introduction can...

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