Emmanuel Peprah is the director of Implementation Science for Global Health and Implementing Sustainable Evidence-based interventions through Engagement (ISEE Lab) at the New York University School of Global Public Health. He has extensive experience developing a portfolio of funded research that addresses the burden of both infectious and non-communicable diseases by utilizing methods that promote the uptake of evidence-based interventions (EBIs) into routine clinical practice and community settings. His research interests lie at the confluence of understanding what, why, and how some EBIs work in some populations and not others in low- and middle-income countries. The programmatic focus of his research is understanding the contextual factors that influence the burden of comorbidity in people living with HIV/AIDS (PWH) with a particular focus on non-communicable diseases including substance abuse. As the burden of non-communicable diseases (NCDs) continue to increase, there is an opportunity to integrate NCD management into HIV care with implementation strategies that leverage the global infrastructure designed to improve care delivery for PWH. Dr. Peprah has built collaborations with diverse and multidisciplinary teams of investigators both nationally and international, to address the high burden of comorbidity in PLW globally. The ISEE Lab also has an interest in utilizing implementation research to increase the delivery of evidence-based interventions to address sickle cell disease (SCD) and obstetric hemorrhage, or OH, in African populations. The mission of the section for SCD at the ISEE lab is to understand the who, why, where and how interventions for SCD management are adopted by certain communities and not others, and ultimately implement sustainable and scalable evidence-based interventions in a context appropriate manner. Because context matters, approaching interventions with cultural sensitivity and innovation for diverse populations in low resource settings, and continuous engagement of key stakeholders is key to improving health and overall health outcomes. Currently, we are examining the evidence in the existing published literature for sickle cell disease management strategies in low-and middle-income countries (LMIC). LMICs, where OH-attributable mortality is highest, there is a growing interest in implementation research as a means to bridge the ‘know-do’ gap between proven interventions and their reliable implementation at scale. The maternal health section of the ISEE lab focuses on implementing EBIs to prevent OH through collaborative implementation research with partners in LMICs. Although, the focus of ISEE is on three overlapping areas of research, Dr. Peprah has a significant interest in health equity and genomic medicine and has published extensively on that subject area.